Sesame review
A high-trust telehealth marketplace that took a clear side: FDA-approved brand GLP-1 only, no compounded shortcut. You pay a brand cash price and book a real video visit — but you get on-label pens and one of the cleaner reputations on our list.
$218/mo with the program (brand pill)
This review draws on the provider’s public pricing, terms and disclosures. No one on this desk is your clinician.
Sesame at a glance
- Semaglutide
- $218/mo with the program (brand pill)
- Tirzepatide
- $368/mo with the program (brand vial)
- Coverage
- All 50 states
- Brand-name
- Yes
How we scored Sesame
Each score comes out of Sesame's published pricing, disclosures and oversight, and the six combine into the 80/100 Editors' Rating on our weighted six-factor framework. A commission never changes a provider's score.
Cost is unpredictable, premium, or hides behind a plan commitment.
Reasonable oversight, though some program details aren't fully public.
Publishes a real, all-in monthly number before you hand over your history.
Workable around a household, though it isn't built around one.
Standard support — enough to stay on track, not high-touch.
Leaving costs you — notice windows, minimum terms or fees you don't get back.
How we verified this review
- Primary source
- Sesame's own site
Sesame has left compounded behind — brand only now. The Wegovy pill is $149 a month at the lower doses and the Zepbound vial starts at $299, but both sit on top of the Success by Sesame program, from $69 a month and billed separately, so a real month starts around $218 for the pill and $368 for the vial. Both prices are posted before you book; settle the renewal and cancellation terms during signup.
What to expect when you sign up
We walked Sesame's public signup — a first-hand look at the flow. We don't create accounts, enter medical data, or complete checkout, so this is what any visitor sees, not a patient outcome.
These signup observations are from . The flow and offers may have changed; use the current pricing and terms in this review.
- 1Self-pay brand prices are posted publicly on the medication page — you can read the number before you book anything
- 2You book an initial video consult with an independent clinician on the marketplace
- 3If prescribed, brand product is routed through the manufacturer's own pharmacy channel (NovoCare for the uninsured)
- 4The Success by Sesame program (from $69 a month, $59 on an annual plan) is billed separately from the medication — note the renewal cadence before you enroll
What we noticed
- This is a marketplace of independent clinicians, not a single-clinic pharmacy — and it no longer sells compounded GLP-1, only FDA-approved brand products
- Brand pens carry the manufacturer's own pregnancy and lactation labeling, which is cleaner to hand an OB than a compounded vial
- BBB complaints report members charged after canceling and refused refunds — confirm the cancellation terms in writing
Pricing
| Medication | Price | Plan |
|---|---|---|
| Brand semaglutide | $218 | Wegovy pill, lower doses (1.5 mg, 4 mg), with program$149 a month for the pill, plus the Success by Sesame program from $69 a month, which is billed separately from the medication ($59 a month on an annual subscription). |
| Brand semaglutide | $368 | Wegovy pill, higher doses (9 mg, 25 mg), with program$299 a month for the pill at maintenance doses, plus the program from $69 a month. |
| Brand semaglutide | $268 → $418 | Wegovy or Ozempic pen, with program$349 a month for the pen ($199 for the first two months for new self-pay patients), plus the program from $69 a month. The Ozempic 2 mg dose is $499 for the medication. |
| Brand tirzepatide | $368 | Zepbound vial, 2.5 mg, with program$299 a month for the vial through the manufacturer's pharmacy, plus the program from $69 a month. |
| Brand tirzepatide | $468 | Zepbound vial, 5 mg, with program$399 a month for the vial, plus the program from $69 a month. |
| Brand tirzepatide | $518 | Zepbound vial, higher doses, with program$449 a month for the vial at every higher dose, plus the program from $69 a month. Zepbound pens run $1,080 to $1,200 a month at a retail pharmacy. |
Swipe the table to see plan details →
GLP-1 telehealth is usually HSA- and FSA-eligible, so check your own plan. Everything above comes from Sesame's public disclosures at last review and change often; confirm the current number on Sesame's own site.
Prices move. Check today's number for your dose.See plans at Sesame
What we like
- FDA-approved brand products (Wegovy pen and pill, Ozempic, Zepbound) with the manufacturer's own labeling
- Self-pay brand prices posted publicly — you can budget before you book
- Strong trust signals: A+ BBB rating and a 4.3/5 Trustpilot average across 1,000+ reviews
- A national marketplace of independent clinicians, available in all 50 states
The caveats
- No longer offers compounded semaglutide or tirzepatide — brand cash prices only
- The program fee, from $69 a month, is billed on top of every medication price
- Requires an initial video visit rather than an async intake
- BBB complaints report members charged after canceling and refused refunds
- A marketplace of independent clinicians, with no single named medical director and no maternal framing
Weighed the likes and the caveats? Look at the plans yourself.See plans at Sesame
Sesame in short
Sesame's posted prices aren't a single all-in monthly rate, so read the pricing below before you compare it. Its strongest marks from us are for price transparency; its weakest are for flexibility to pause or cancel.
Lab work is included in the program.
What Sesame actually costs
- Brand-name semaglutide — Wegovy pill, lower doses (1.5 mg, 4 mg), with program: $218/mo
- Brand-name semaglutide — Wegovy pill, higher doses (9 mg, 25 mg), with program: $368/mo
- Brand-name semaglutide — Wegovy or Ozempic pen, with program: $268 to start, then $418/mo
- Brand-name tirzepatide — Zepbound vial, 2.5 mg, with program: $368/mo
- Brand-name tirzepatide — Zepbound vial, 5 mg, with program: $468/mo
- Brand-name tirzepatide — Zepbound vial, higher doses, with program: $518/mo
There is no compounded tier here to set against the roughly $196/month typical price among the providers we've reviewed — the figures above are a fee for the service, with an FDA-approved brand medication billed on top. Price the two together before you compare this to anything else on the board. Higher doses cost more here; plan around the price at your maintenance dose, not the starting one.
The price covers the clinician consult and lab work. The medication is not included, so add that to the total.
The medications Sesame prescribes
Sesame prescribes semaglutide and tirzepatide — the two GLP-1 medications with the strongest evidence. If insulin resistance is part of your story (PCOS, a history of gestational diabetes), tirzepatide is often the better fit, and you won't need a new provider to try it. Brand-name pens are available too, and their official labeling on pregnancy and breastfeeding is easier to discuss with an OB than a compounded vial.
Getting started
Sesame treats patients in all 50 states. Expect a video visit with a clinician before anything is prescribed — harder to fit into a full day, but a real conversation.
Similar providers
Other providers we've reviewed that offer semaglutide and tirzepatide:
- AquaVita NextGen — $215/mo, semaglutide and tirzepatide, same price at every dose
- Tyde Wellness — no comparable monthly rate confirmed, semaglutide and tirzepatide, same price at every dose
- Alinwell — $139/mo, semaglutide and tirzepatide, same price at every dose
Where Sesame fits — and where it doesn't — for mothers
A good fit if…
- You want a clinician who actually reads your history, not a quiz that approves everyone.
- You'd like the option to move to tirzepatide (or back) without changing providers.
- You need a provider that works wherever you live.
Look elsewhere if…
- You want to be able to cancel easily — read the cancellation terms in the cons first.
- You're planning another baby and want that timing discussed before you start — compare CoreAge Rx, a featured partner.
Safety and oversight
With brand-name medication, ask which pharmacy dispenses it and whether your insurance or a savings card applies. Our Editors' Rating methodology explains how we score oversight.
Tell your own clinician if you are pregnant, breastfeeding or trying to conceive before starting treatment. Using medication for weight loss is not recommended while pregnant. Breastfeeding decisions require the specific product’s labeling and an individual assessment, rather than a blanket rule across every GLP-1 formulation.
Before you pay, ask
- What will I pay each month, and does that change as the dose goes up?
- How do I cancel, and is there a minimum term?
- How soon can I book the video visit?
- If I get pregnant or start trying, how do I pause, and will I be charged meanwhile?
Our take
Without one all-in monthly price, Sesame is hard to judge on cost. Its strongest point with us is price transparency; get a quote before you weigh it against the rest. CoreAge Rx, a featured partner, is worth a side-by-side look before you decide.
The bottom line for mothers
Best for: Mothers who specifically want an FDA-approved brand GLP-1 with its own pregnancy and lactation labeling, from a high-trust marketplace, and are willing to pay a brand cash price for it.
Alternatives to Sesame
These are partners — we may be paid if you sign up through these links. The full list has every provider we cover, partner or not.
- Visit CoreAge RxCoreAge RxFeatured partner
The one program on our list whose number still makes sense at the top of the dose. A flat, all-in monthly price on both molecules, no teaser rate to expire, and a cancel button you can actually find — the closest thing to a family-budget guarantee we've reviewed.
- Visit Oak
A flat, all-dose compounded price with an oral option and a genuinely thorough intake — undercut by a headline that isn't the real month-to-month number and terms that lock you in hard once the box ships.
- Visit Wellorithm
Compounded semaglutide and tirzepatide, plus brand-name pens, sold in 49 states — but the compounded prices appear only once you start the intake, and the brand prices assume three months paid upfront.
Providers like Sesame
Keep comparing Sesame
Head-to-head & alternatives
Ranked boards
- The 2026 guide to the best GLP-1 for moms
- Best GLP-1 for women — PCOS & menopause
- Best GLP-1 for first-timers & beginners
- Cheapest GLP-1 without insurance
- Best GLP-1 after baby — postpartum providers ranked
- Best GLP-1 with insurance & coverage help
- Best GLP-1 providers for PCOS
- Best GLP-1 for perimenopause & menopause
- Cheapest tirzepatide online, month to month
- Cheapest semaglutide online, month to month
Sesame, answered
- Does Sesame still offer compounded semaglutide?
- No. Sesame was among the first big platforms to ship compounded semaglutide nationwide back in 2024, but that offering has been discontinued — it now lists FDA-approved brand products only: the Wegovy pen and pill, Ozempic, and Zepbound. For a mother, that changes the math: you're paying brand self-pay prices (the Wegovy pill is $149 a month at the lower doses, plus the Success by Sesame program from $69 a month), not a cheap compounded rate, but you're also getting an on-label product with the manufacturer's own labeling.
- Is Sesame a trustworthy place for a mother to start?
- On the trust signals we check, Sesame is one of the stronger names on our list: an A+ BBB rating for the company and a 4.3/5 Trustpilot average across more than a thousand reviews. The caveat worth naming is billing — BBB complaints report members charged after they canceled and then refused refunds. Sesame runs on a recurring membership, so read the renewal and cancellation terms before you enroll, and keep a copy.
- Why does brand access matter for a mother specifically?
- Compounded semaglutide and tirzepatide aren't FDA-approved finished products the way Wegovy, Ozempic and Zepbound are, so they don't carry the manufacturer's own pregnancy and lactation labeling. If you specifically want an on-label pen to hand your OB — and you'd rather not weigh a compounding pharmacy's formulation — Sesame's brand-only marketplace is built for exactly that, at a brand-cash price. No GLP-1, brand or compounded, is established as safe while breastfeeding; plan the timing with your clinician.
Have a question we didn't answer? Sesame's team can.See plans at Sesame
Pricing, states and verification reflect Sesame's public disclosures at last review; the Editors' Rating is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.