For first-timers · Updated October 2026
The first GLP-1 is the one where a good program earns its keep — gentle titration, a real person to text when the nausea hits, and a price that isn't a puzzle while you're still learning what any of this means. We ranked the field for exactly that.
The short answer
CoreAge Rx, a featured partner, scores 94/100: nothing to decode, a flat price, and support that follows you up the dose ladder. If you want more hand-holding, Found offers the most coaching of the partners we work with. Providers we work with may appear first, and every provider here is scored on the same six-factor rubric.
CoreAge Rx is a featured partner, and providers we work with may appear first. Scores are our own — the Editors’ Rating is printed on every row so you can check it.
The one program on this masthead whose number still makes sense at the top of the dose. A flat, all-in monthly price on both molecules, no teaser rate to expire, and a cancel button you can actually find — the closest thing to a family-budget guarantee we've reviewed.
One price at every dose: $249 for semaglutide or $299 for tirzepatide month to month, falling to $199 on three months and $129 or $179 on a prepaid year — a reasonable all-doses-included option, if you can live with a pharmacy the marketing never names.
One of the better-disclosed cash compounders we've reviewed for mothers — a named medical director, named pharmacies and real Quest lab work behind flat-per-dose pricing. The catch is that the low headline number you'll see quoted is the 12-month prepay rate, not the month-to-month price.
A women's-health company by contract, not just by campaign — it names its pharmacies, names its physicians, and prints both prices before the quiz. Then the dose ladder disappears behind the intake and the refund policy changes depending which of its own pages you read.
A high-trust telehealth marketplace that took a clear side: FDA-approved brand GLP-1 only, no compounded shortcut. You pay a brand cash price and book a real video visit — but you get on-label pens and one of the cleaner reputations on this masthead.
The rare program that will write you either a compounded vial or an FDA-approved pen and bill the visit through your insurance, holding one price at every dose. The catch is the calendar: the cheap headline needs a year paid upfront, and every refill needs a video call.
A women's-condition clinic that happens to prescribe GLP-1s, rather than a weight-loss program wearing a women's-health skin — an OBGYN and a dietitian on every case, real labs, and an every-other-week check-in for a flat $149 with no commitment. The drug is not in that number, and Allara writes brand pens only.
The one program on this masthead that treats menopause and the postpartum year as clinical facts rather than marketing, wrapped around brand-name pens and an insurance coordinator who makes the calls. Then it sells you a year you cannot leave.
Maven Clinic built its name on maternity, fertility and menopause care sold through employers, and its new self-pay GLP-1 program brings that women's-health depth to weight care. You pay a $150 monthly membership ($39 the first month) for unlimited clinician support, a nutrition coach and a strength coach, plus FDA-approved medication billed by the pharmacy — about $299 a month all-in for the Wegovy pill and $449 for starting-dose Zepbound. Every dose has a published price, which is rare, but the two-charge structure makes it one of the pricier ways to start.
FDA warning letters dated 9 September 2025, over the compounded-semaglutide business it has since left behind. Through the Hers front door, a mass-market brand now selling FDA-approved brand-name GLP-1s — Wegovy, Zepbound, Ozempic — instead of the compounded semaglutide it used to. The posted price is only half the bill: a required $149/mo membership sits on top of whatever the medication costs, so the real monthly number is roughly double what the landing page shows.
A nationwide, physician-led program that has shifted from compounded to brand-name medication now that the FDA shortage exemption has ended — a disclosed $149/mo membership plus a separately billed drug cost, honest about the shift even where the number is bigger than it used to look.
The only program on this masthead that bills insurance, which changes the arithmetic more than any discount here. The visit is covered in network or costs $250 self-pay, and the medication is billed separately from $165.90 per four-week supply for injectable semaglutide and $210 for tirzepatide — both the visit fee and a full dose table published, which is what makes the model reviewable at all.
The best-funded option on the board: real brand-name Wegovy and Zepbound access, a dedicated insurance concierge, and an app that rarely breaks — with the catch that the membership fee and the medication cost are always two separate charges, and it doesn't say whether check-ins are video or async.
Midlife-focused weight care with physician messaging and both compounded and FDA-approved brand options. Add the required $99 monthly care fee: compounded semaglutide starts at $169 all-in and tirzepatide at $199. These are starting figures, not a published maintenance-dose ladder. Compounds are unavailable in six states and DC.
The closest thing on this masthead to an actual obesity-medicine clinic online — a board-certified physician and a registered dietitian on your case, monthly video visits, and a real effort to run treatment through your insurance. The $299 self-pay fee is for that care team, not the medication.
One of the only programs on our list offering both molecules as an injection AND a needle-free oral tablet, in all 50 states — but its $179/mo semaglutide headline is a stated summer promo, not a locked-in rate, and its "15-22% weight loss" claim is self-reported customer data, not a clinical trial.
Flat, all-dose compounded pricing with an honest footnote: the $99 semaglutide headline is the annual-prepay rate, and month to month is $175, so read the plan terms before the headline number.
Weightstry's GLP-1 program combines clinician access with biweekly coaching and a midlife focus. The ongoing FAQ prices are $249 for semaglutide and $339 for tirzepatide per four weeks; lower grid prices are starting offers. Care is currently waived during a promotion, so confirm the total after that waiver. Louisiana is waitlisted.
A year-long metabolic program that treats the medication as one lever and intensive human coaching as the other — a disclosed $199/mo membership with a 3-month minimum, a real 20-minute video visit, and insurance doing most of the work on the medication itself.
Starts at $189/mo for semaglutide or $199/mo for tirzepatide, $40 less on your first order, and scales up with your dose to $299–$389/mo at the top tier. A $199 oral tablet and brand-name Wegovy and Zepbound are also available, in 48 states (all but AL and MS), with a cancel-or-pause-anytime policy.
The rare compounded program that names its doctors and puts a real 30-minute video visit in front of the prescription — and then prices itself in two pieces, so the $60 on the front page is well under half what leaves your account once the $79 clinic fee is added.
The $99 a month in the banner is real, but it is a year paid at once — $1,188. Month to month, compounded semaglutide is $279.99 after a $179.99 first month, flat at every dose, and nothing ever renews without your say-so.
The weight-loss app many of us already know, now with prescribers and a long medication list: compounded microdose semaglutide or tirzepatide, full-dose compounded tirzepatide, and brand-name Wegovy, the Wegovy pill, Zepbound, Ozempic, Mounjaro and Foundayo. The microdose plan is $79 to start, then $179 a month on a 12-week subscription with medication included. Full-dose tirzepatide is $299 a month after a $149 start. Brand-name care starts at $39, then runs $129 a month, with the medication billed separately or through insurance. Every price lives in a footnote, and the footnotes carry different dates, so screenshot the one you sign up under. The compounded plans are not offered in every state, and no state list is published.
Founded by named former clinic owners, with no consultation or membership fees, 24/7 messaging and Zofran offered proactively for nausea — $155/mo semaglutide or $229/mo tirzepatide at any dose, published on a clear pricing page, though only its pharmacy's licensing (not Bodi Envi's own) is confirmed in all 50 states.
A cardiometabolic telehealth platform — diabetes and weight management together — with a $149/mo membership (or no fee if your insurance covers it) for specialist visits, labs, devices and coaching. It prescribes only FDA-approved brand GLP-1s (Wegovy, Zepbound, Saxenda), and what that medication costs you depends on your insurance; no out-of-pocket price is published. There is no state list, and its own branding leans more toward diabetes than weight loss.
| # | Provider | From | States | Rating |
|---|---|---|---|---|
| 1 | CoreAge Rx | $99/mo | All 50 states | 94 · A |
| 2 | Gala Health | $249/4 wk | All 50 states | 82 · B− |
| 3 | Enhance MD | $249/mo | 40 states | 80 · B− |
| 4 | Willow | $299/mo | 36 states | 71 · C |
| 5 | Sesame | See review | All 50 states | 80 · B− |
| 6 | Found | $289/4 wk | See review | 76 · C |
| 7 | Allara Health | See review | 45 states | 83 · B |
| 8 | WeightWatchers Clinic | See review | See review | 78 · C |
| 9 | Maven Clinic | See review | See review | 74 · C |
| 10 | Hims & Hers | See review | All 50 states | 76 · C |
| 11 | LifeMD | See review | All 50 states | 80 · B− |
| 12 | Midi Health | $165.9/4 wk | All 50 states | 80 · B− |
| 13 | Ro | See review | All 50 states | 80 · B− |
| 14 | Alloy | $169/mo | See review | 73 · C |
| 15 | Form Health | See review | See review | 81 · B− |
| 16 | OnlyRx | $179/mo | All 50 states | 70 · C |
| 17 | Trimi Health | $175/mo | All 50 states | 81 · B− |
| 18 | Fitstry | $249/4 wk | 49 states | 68 · C |
| 19 | Calibrate | See review | See review | 79 · C |
| 20 | WePeptideRx | $189/mo | 48 states | 78 · C |
| 21 | Mochi Health | $139/mo | All 50 states | 77 · C |
| 22 | Rx.com | $279.99/mo | 49 states | 68 · C |
| 23 | Noom Med | See review | All 50 states | 64 · C |
| 24 | Bodi Envi | $155/mo | All 50 states | 70 · C |
| 25 | 9amHealth | See review | See review | 66 · C |
CoreAge Rx, a featured partner, is shown first on our beginner board at 94/100 — a flat, all-in price with no surprises to decode while you're learning the ropes, plus support that stays with you as the dose climbs. If you want more coaching, Found is the most hand-holding of the partners we work with. Providers we work with may appear first; scores are our own.
You start at the lowest dose and titrate up slowly, usually monthly, to limit nausea. Early side effects are mostly gastrointestinal — nausea, constipation, reflux — and tend to ease as your body adjusts. A good beginner program checks in during this window and helps you manage it rather than leaving you to guess.
The injections use a very fine, short needle and most first-timers find them far easier than expected. Some providers also offer oral or sublingual routes, which can be a gentler on-ramp. Either way, look for a program that walks you through your first dose rather than shipping a pen and wishing you luck.
Reputable programs review your history and often baseline labs before prescribing, and they should ask about thyroid history, pregnancy plans and contraception. If a provider will prescribe with almost no questions, treat that as a warning sign, not convenience.
Before your first dose, read what to tell your OB and the true cost as the dose climbs. Comparing on price alone? See the cheapest GLP-1 without insurance, or the full 2026 guide for moms. This page is informational, not medical advice; compounded medications are not FDA-approved brand products.
Keep exploring
Each board answers a different mother's situation. CoreAge Rx is a featured partner, and providers we work with may appear first.