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Grade C

Clume Health review

Clume names four dispensing pharmacies outright and tells you who prescribes, which almost nothing else here does, and it charges the same price whichever molecule you pick — $259 a month on the full-dose Signature program, $219 on maintenance and microdosing, semaglutide or tirzepatide, oral or injectable. For a family set on the dual agonist that is worth real money, since most sellers add $80 to $150 a month for it. The pricing you meet first is where it goes wrong. The homepage advertises programs starting at $199 and $159, nothing on the site is priced at either, and the asterisks beside both lead to no footnote anywhere on the page. The cheaper rates it does publish are prepaid terms rather than monthly bills: $186 a month means committing 52 weeks and $200 means twelve. Canceling needs 72 hours' notice before the next billing date or that cycle is charged anyway, and no refund is given for the month you cancel or any month before it.

$259/mo
Flat price · every dose
Consult Medication
See plans at Clume Health
  • Six-factor Editors' Rating
  • Source-based review
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By Margaux Ellery, Editor-in-Chiefa mother on the MetabolicMoms desk, not a treating clinician

This review draws on the provider’s public pricing, terms and disclosures. No one on this desk is your clinician.

Clume Health at a glance

Semaglutide
$259/mo
Tirzepatide
$259/mo
Coverage
Not published
Brand-name
Compounded only

How we scored Clume Health

Each score comes out of Clume Health's published pricing, disclosures and oversight, and the six combine into the 44/100 Editors' Rating on our weighted six-factor framework. A commission never changes a provider's score.

Family-budget value45/100 · Weak

Cost is unpredictable, premium, or hides behind a plan commitment.

Clinical oversight & labs62/100 · Weak

Oversight and lab support fall short of the best we track — the review below says exactly where.

Pricing transparency35/100 · Weak

The headline rate obscures a plan requirement or a hidden step-up.

Fits around motherhood30/100 · Weak

Little here is shaped around a mother's week or her life stage.

Ongoing support & titration55/100 · Weak

Support is thin once the prescription ships.

Flexibility to pause or cancel30/100 · Weak

Leaving costs you — notice windows, minimum terms or fees you don't get back.

How we verified this review

Primary source
The company's own site

It names four dispensing pharmacies outright, which almost no compounded seller does, and it charges the same whichever molecule you choose — $259 a month on the full-dose program and $219 on maintenance and microdosing, semaglutide or tirzepatide, oral or injectable. The pricing you meet first is not the pricing you can buy. The homepage advertises programs starting at $199 and $159 and nothing costs either figure, with asterisks that lead to no footnote at all. The cheaper published rates are prepaid terms: $186 a month means committing a full 52 weeks. Canceling needs 72 hours' notice or that cycle is billed, and no month is refunded.

Pricing

MedicationPricePlan
Compounded semaglutide$259Signature program, full dose, month to monthThe rate you can actually pay month to month. The $186 advertised beside it requires prepaying a 52-week term.
Compounded tirzepatide$259Signature program, full dose, month to monthIdentical to semaglutide — Clume prices by program rather than by molecule, so the dual agonist costs no more.
Compounded semaglutide$219Microdose/Maintain program, month to monthThe maintenance and microdosing track. Its cheaper $200 rate requires a 12-week prepaid term.
Compounded tirzepatide$219Microdose/Maintain program, month to monthAgain the same price as semaglutide on the same program.

Swipe the table to see plan details →

GLP-1 telehealth is usually HSA- and FSA-eligible, so check your own plan. Everything above comes from Clume Health's public disclosures at last review and change often; confirm the current number on Clume Health's own site.

What we like

  • Names four dispensing pharmacies outright, which most compounded sellers never do
  • Names OpenLoop as the prescribing layer rather than leaving the clinical relationship vague
  • The same price for semaglutide or tirzepatide, oral or injectable
  • A separate maintenance and microdosing program at a lower rate
  • Names its operating company, North Atelier LLC, in its own terms

The caveats

  • The homepage advertises "starting at *$199/month" and "*$159/month" and no program costs either
  • Those asterisks lead to no footnote anywhere on the page
  • The cheapest advertised rates require prepaying a full term — $186/mo means 52 weeks
  • Canceling needs 72 hours' notice before the next billing date or that cycle is charged
  • No refund for the month you cancel, or for any prior month
  • No state list published, and nothing addresses pregnancy, breastfeeding or postpartum timing

Is Clume Health worth it?

Clume Health costs about $259/month, more than most providers charge. Where it earns its score is clinical oversight. Where it loses ground is flexibility to pause or cancel.

What Clume Health actually costs

  • Compounded semaglutide — Signature program, full dose, month to month: $259/mo
  • Compounded tirzepatide — Signature program, full dose, month to month: $259/mo
  • Compounded semaglutide — Microdose/Maintain program, month to month: $219/mo
  • Compounded tirzepatide — Microdose/Maintain program, month to month: $219/mo

For comparison, the typical price we see is about $196/month — Clume Health sits above it. Over a year at that rate, you'd spend about $3,108. The price is the same at every dose, so the bill doesn't grow as you step up.

What's included: the clinician consult and the medication.

What Clume Health prescribes

Clume Health prescribes semaglutide and tirzepatide. Tirzepatide often suits women whose weight is tied to insulin resistance — common after PCOS or gestational diabetes — so having both options on one account is useful. The medication is compounded by a licensed pharmacy rather than an FDA-approved brand pen — cheaper, but not reviewed by the FDA as a finished product.

A needle-free option is on the menu, which appeals if injections have been the sticking point. The catch is evidence: oral and sublingual versions of these peptides are much less studied than the injectable ones.

Before you start the intake

There's no published list of states, so confirm yours before you share any health details.

Alternatives to Clume Health

Close in price to Clume Health, and worth comparing:

  • The Edit — $259/mo, semaglutide and tirzepatide, same price at every dose
  • Prime Doctor RX — $249/4 wks, semaglutide and tirzepatide, same price at every dose
  • yourEra — $79/mo, semaglutide and tirzepatide, same price at every dose

Is Clume Health right for you?

A good fit if…

  • You may want to switch between semaglutide and tirzepatide later on.

Look elsewhere if…

  • You specifically want an FDA-approved brand pen with its own pregnancy and breastfeeding labeling.
  • You need a no-strings plan; the cancellation fine print here is worth reading before you sign up.
  • Budget is tight — it costs more than most of the providers we've reviewed.
  • You need to know up front whether it treats patients in your state — it doesn't publish a state list.

Can you trust it?

With any compounded GLP-1, ask which licensed pharmacy fills the prescription and what exactly is in the vial. Our Editors' Rating methodology explains how we score oversight.

Weight-loss treatment is not recommended during pregnancy. If you are breastfeeding or planning pregnancy, discuss the exact medicine, formulation and timing with your own clinician; limited milk-transfer data do not establish infant safety.

What to ask Clume Health first

  • Do you treat patients in my state?
  • How do I cancel, and is there a minimum term?
  • Can I pause the plan if we decide to try for a baby?

The bottom line

Clume Health costs more than most, so it has to earn the difference — its strongest card is clinical oversight. CoreAge Rx, a featured partner, is worth a side-by-side look before you decide.

The bottom line for mothers

Best for: A family that wants tirzepatide without paying a premium for it, and that cares enough about who compounds the medication to choose a seller which says so.

Alternatives to Clume Health

These are partners — we may be paid if you sign up through these links. The full list has every provider we cover, partner or not.

  • CoreAge RxFeatured partner

    The one program on our list whose number still makes sense at the top of the dose. A flat, all-in monthly price on both molecules, no teaser rate to expire, and a cancel button you can actually find — the closest thing to a family-budget guarantee we've reviewed.

    Visit CoreAge Rx
  • A women's-health company by contract, not just by campaign — it names its pharmacies, names its physicians, and prints both prices before the quiz. Then the dose ladder disappears behind the intake and the refund policy changes depending which of its own pages you read.

    Visit Willow
  • Flat pricing across dose escalations is a genuine virtue, and it sits under a landing page advertising a first-month rate as if it were the price, two brand-name drugs you cannot buy, and no mention of pregnancy anywhere. The FDA letter is about exactly that habit.

    Visit Sprout Health

Providers like Clume Health

Keep comparing Clume Health

Clume Health, answered

Why does the homepage price match nothing?
Because it matches nothing. The homepage advertises GLP-1 and microdose programs "starting at *$199/month" and cellular optimization "starting at *$159/month", and no program on the site is priced at either. The asterisks that should explain the gap lead to no footnote anywhere on the page. The real menu opens at $259 for the full-dose program and $219 for maintenance and microdosing.
Does tirzepatide cost more here?
No, and that is genuinely unusual. Clume prices by program rather than by molecule, so $259 buys the full-dose Signature program whether you take semaglutide or tirzepatide, in oral or injectable form. Most sellers charge $80 to $150 more a month for the dual agonist, so anyone set on tirzepatide should notice this.
What does $186 a month require?
A 52-week commitment. The $186 rate on Signature and the $200 rate on Microdose/Maintain are prepaid terms, not lower monthly bills — 52 weeks and 12 weeks respectively. If you want to keep the option of stopping, budget $259 and $219.
Who prescribes and who compounds?
Clume names both, which is rare. The prescribing layer is OpenLoop — the intake requires agreeing to OpenLoop's telehealth consent and the terms reference OpenLoop Medical Practices — and the terms name four dispensing pharmacies outright rather than calling them accredited partners. The operating company is North Atelier LLC, trading as Clume Health, under Iowa law.

Pricing, states and verification reflect Clume Health's public disclosures at last review; the Editors' Rating is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.

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