Rx.com review
One of the very few programs that shows a household the entire price table before asking for anything. Compounded semaglutide is $175 a month with no commitment; the advertised $146 is $875 prepaid for six months.
- Independently scored
- Verified
Every medical claim in this piece is footnoted to the record it came from — the trial or the FDA label — so you can read the source rather than take the masthead's word for it. No one on this desk is your clinician.
Rx.com at a glance
- Semaglutide
- $175/mo
- Tirzepatide
- $285/mo
- Coverage
- 49 states — all except Alaska, per its own FAQ
- Brand-name
- Compounded only
How we scored Rx.com
Each score comes out of Rx.com's published pricing, disclosures and oversight, and the six combine into the 76/100 Editors' Rating on the same weighted six-factor framework we apply to every provider — never nudged by whether a provider pays us.
Cost is unpredictable, premium, or hides behind a plan commitment.
Oversight and lab support fall short of the top of this roster — the review below says exactly where.
The core price is disclosed, but some conditions or add-ons aren't upfront.
Little here is shaped around a mother's week or her life stage.
Standard support — enough to stay on track, not high-touch.
Easy to pause and cancel — important when a mother's plans shift.
How we verified this review
- Last verified
- September 2026
- Confidence
- high
- Primary source
- rx.com
$175 and $285 month to month, flat at every dose, with the visit, syringes and cold shipping inside. The advertised $146 is the six-month prepay — $875 at once. Nothing renews on its own: the care team confirms before every refill. Coverage is 49 states, with Alaska excluded.
Pricing
Prices re-verified
| Medication | Monthly | Plan |
|---|---|---|
| Compounded semaglutide | $175 | Any dose, month to monthThe one-month plan, $175 in a single payment. This is the figure a household can pay as it goes, without committing anything. |
| Compounded semaglutide | $165 | Any dose, 3-month plan$495 in one payment, not a monthly rate. |
| Compounded semaglutide | $146 | Any dose, 6-month plan⛔ THIS IS THE ADVERTISED $146 — $875 up front for six months. The homepage badges it as an "Exclusive Lifetime Offer" without saying on the same line that the half-year is prepaid. |
| Compounded tirzepatide | $285 | Any dose, month to monthThe one-month plan, $285 in a single payment. |
| Compounded tirzepatide | $265 | Any dose, 3-month plan$795 in one payment. |
| Compounded tirzepatide | $259 | Any dose, 6-month plan$1,550 in one payment — the source of the $259 that appears in comparisons. |
Swipe the table to see plan details →
GLP-1 telehealth is usually HSA- and FSA-eligible, so check your own plan. Everything above comes from Rx.com's public disclosures at last review and change often; confirm the current number on Rx.com's own site.
What we like
- The entire price table is published before any intake
- Flat pricing at every dose, with the milligram ranges published
- Nothing renews automatically — the care team confirms before every refill
- Visit, syringes, cold shipping and unlimited messaging are inside the price
- Names the excluded state rather than promising all fifty
- Names its operating company, Rx Platform LLC, in its own terms
The caveats
- The advertised $146 is the six-month plan, $875 in a single payment
- The homepage badge promises 50 states while the program FAQ says 49
- Alaska is excluded, and some states add a required video visit
- Shipped medication cannot be returned
- No brand-name path — compounded only
- Nothing addresses pregnancy, breastfeeding or postpartum timing
Rx.com for mothers: our verdict
One of the very few programs that shows a household the entire price table before asking for anything. Compounded semaglutide is $175 a month with no commitment; the advertised $146 is $875 prepaid for six months. It runs about $175/month, flat across every dose.
We weigh Rx.com the way mothers actually have to: not just the real monthly cost, but the real monthly cost once the dose climbs and whether a real clinician stands behind it — the things a generic roundup never gets to.
What Rx.com actually costs
- Compounded semaglutide — Any dose, month to month: $175/mo
- Compounded semaglutide — Any dose, 3-month plan: $165/mo
- Compounded semaglutide — Any dose, 6-month plan: $146/mo
- Compounded tirzepatide — Any dose, month to month: $285/mo
- Compounded tirzepatide — Any dose, 3-month plan: $265/mo
- Compounded tirzepatide — Any dose, 6-month plan: $259/mo
That's roughly in line with the ~$179/month median across our roster.
The medications Rx.com prescribes
Rx.com prescribes semaglutide and tirzepatide — the pair with the strongest evidence behind them, and having both under one account matters when insulin resistance, familiar from PCOS and gestational diabetes, makes tirzepatide the better fit. These are compounded formulations from a licensed pharmacy — the reason the price stays down — but compounded GLP-1s aren't FDA-approved finished products the way Wegovy and Zepbound are.
Where Rx.com fits — and where it doesn't — for mothers
Worth it if…
- the real monthly cost is a real barrier and you want a low, predictable number.
- you may need to move between semaglutide and tirzepatide as your body and hormones change.
Give it a miss if…
- you specifically want an FDA-approved brand pen with its own pregnancy and lactation labeling.
- you'd rather a prescriber talk through timing around the real monthly cost once the dose climbs — that's what our #1 pick, CoreAge Rx, is built for.
Trust, safety, and oversight
Our confidence in Rx.com's public facts is high — pricing, pharmacies, and clinical network were verifiable at last review. As with any compounded GLP-1, the most useful thing mothers can do is confirm which licensed pharmacy fills the prescription and what's in the formulation — we explain how we weigh oversight in our Editors' Rating methodology.
A standing caveat for mothers: GLP-1 medications aren't established as safe during pregnancy or breastfeeding, and every label advises against use. Nothing here changes that — plan the timing with your own clinician.
The bottom line
Rx.com is a reasonable option — weigh it on the real monthly cost once the dose climbs and whether a real clinician stands behind it against the alternatives below. For most mothers, CoreAge Rx remains the stronger all-round fit — see why it tops our ranking.
The bottom line for mothers
Best for: A household that wants the full price table before handing over a detail, and that values never being charged automatically more than it values the lowest possible figure.
Alternatives to Rx.com
Providers we have a referral relationship with, ordered by their Editors' Rating — highest first. A fee never moves a rating, but it does decide who appears here, so this is not the whole roster: the full ranking lists every provider we cover.
- Visit CoreAge RxCoreAge RxOur #1 pick
The one program on this masthead whose number still makes sense at the top of the dose. A flat, all-in monthly price on both molecules, no teaser rate to expire, and a cancel button you can actually find — the closest thing to a family-budget guarantee we've reviewed.
- Visit Gala Health
A flat $179 for either molecule and a genuinely gentle microdosing tier — a reasonable, all-doses-included option, if you can live with a yearly plan and a pharmacy the marketing never names.
- Visit Sesame
A high-trust telehealth marketplace that took a clear side: FDA-approved brand GLP-1 only, no compounded shortcut. You pay a brand cash price and book a real video visit — but you get on-label pens and one of the cleaner reputations on this masthead.
Keep comparing Rx.com
Head-to-head & alternatives
Rx.com, answered
- Is it really $146 a month?
- Only with six months prepaid. The $146 is the six-month plan, billed as $875 in a single payment. Month to month, compounded semaglutide is $175 and can be stopped at any time. The advertised figure is real, but it is an $875 decision rather than a monthly one — worth knowing before the first click.
- Will the plan charge automatically?
- No, and Rx.com is unusually direct about it. Its own page states the plan does not renew automatically and that nothing ships or is charged until the patient confirms with the care team before each refill. Canceling carries no fee. The only irreversible part is medication that has already shipped, which cannot be returned.
- Does the price rise as the dose climbs?
- No. The same figure applies from 0.25 to 2.4 mg of semaglutide and from 2.5 to 15 mg of tirzepatide, and the ranges are published rather than implied. That matters most in the first months, when the dose almost always climbs and many programs let the bill climb with it.
- Is it available everywhere?
- Not quite. The program FAQ says 49 states, all except Alaska, and adds that some states require a short video visit handled during intake. The homepage badge still reads all 50 states, so the two disagree — the FAQ is the more specific of the two and the one to plan around.
- Is it safe while pregnant or breastfeeding?
- No. Rx.com's own safety information excludes pregnancy, breastfeeding and anyone planning a pregnancy, and that applies to every GLP-1 this magazine covers. Anyone in one of those three situations should be talking to their obstetrician or pediatrician first, not comparing telehealth prices.
Pricing, states and verification reflect Rx.com's public disclosures at last review; the Editors' Rating is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.