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Grade C

Joi + Blokes review

A women's hormone and wellness brand (Joi, with a men's side called Blokes) that also sells compounded GLP-1s: semaglutide at $179 a month and tirzepatide at $249, with the first month at $99 or $149. The price includes medication, clinician consults and a health coach you can message. Billing is quarterly, and while the product page says cancel anytime, the Terms set a three-month minimum. It also holds a June 2026 FDA warning letter over how it marketed compounded semaglutide and tirzepatide. Brand-name Zepbound is available as a $99-a-month program, with the vials bought separately from LillyDirect. The same company offers HRT, thyroid care and lab panels, which helps if weight is only one piece of what changed.

$99to start

then $179/mo ongoing

Flat price · every dose
Consult Medication Coaching
See plans at Joi + Blokes
  • Six-factor Editors' Rating
  • Source-based review
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By Margaux Ellery, Editor-in-Chiefa mother on the MetabolicMoms desk, not a treating clinician

This review draws on the provider’s public pricing, terms and disclosures. No one on this desk is your clinician.

Joi + Blokes at a glance

Semaglutide
$179/mo
Tirzepatide
$249/mo
Coverage
Most states; compounded semaglutide is not available in every state, and NY and NJ are priced differently
Brand-name
Yes

How we scored Joi + Blokes

Each score comes out of Joi + Blokes's published pricing, disclosures and oversight, and the six combine into the 63/100 Editors' Rating on our weighted six-factor framework. A commission never changes a provider's score.

Family-budget value64/100 · Weak

Cost is unpredictable, premium, or hides behind a plan commitment.

Clinical oversight & labs66/100 · Weak

Oversight and lab support fall short of the best we track — the review below says exactly where.

Pricing transparency56/100 · Weak

The headline rate obscures a plan requirement or a hidden step-up.

Fits around motherhood74/100 · Fair

Little here is shaped around a mother's week or her life stage.

Ongoing support & titration76/100 · Fair

Support is thin once the prescription ships.

Flexibility to pause or cancel40/100 · Weak

Leaving costs you — notice windows, minimum terms or fees you don't get back.

How we verified this review

Primary source
The company's own site

Compounded semaglutide at $179 a month and tirzepatide at $249, with a cheaper first month, billed quarterly with a three-month minimum. It holds a June 2026 FDA warning letter over how it marketed compounded GLP-1s.

Pricing

MedicationPricePlan
Compounded semaglutide$99 → $179"$179/mo (first month $99) billed quarterly." Includes the medication, dosing support, clinician consultations and health coaching. The Terms set a three-month minimum on subscriptions.
Compounded tirzepatide$149 → $249"$249/mo (first month $149) billed quarterly", with the same inclusions and the same three-month minimum.
Brand tirzepatide$448Zepbound 2.5 mg vial plus the $99 programThe Zepbound program is $99 a month ($297 per three months) and does not include the medication. Joi's page lists the LillyDirect vial prices as $349 for 2.5 mg, $499 for 5 mg, $599 for 7.5 mg and $699 for 10 mg, paid to LillyDirect directly. LillyDirect sets those prices, so check its own page.

Swipe the table to see plan details →

GLP-1 telehealth is usually HSA- and FSA-eligible, so check your own plan. Everything above comes from Joi + Blokes's public disclosures at last review and change often; confirm the current number on Joi + Blokes's own site.

What we like

  • Medication, clinician consults and coaching in one published price
  • Hormone therapy, thyroid care and labs from the same company
  • Unlimited messaging with a care team and a health coach
  • Brand-name Zepbound program with the medication bought straight from LillyDirect
  • HSA and FSA accepted, and a refund if a clinician decides not to prescribe

The caveats

  • FDA warning letter to Joi and Blokes dba Joi + Blokes, dated June 8, 2026, over its marketing of compounded semaglutide and tirzepatide
  • The Terms set a three-month minimum even though the product page says cancel anytime
  • Billed quarterly, so the first charge covers three months
  • Products are non-refundable once shipped, under the Terms
  • Care comes from independent partner clinician groups rather than Joi + Blokes' own clinicians
  • Compounded semaglutide is not available in every state, and no list is published

Joi + Blokes for mothers: our verdict

Joi + Blokes advertises $99 to start, but the regular rate is about $179/month — that second number is the one to budget for. Its strongest marks from us are for support as your dose changes; its weakest are for flexibility to pause or cancel.

Both brand-name and compounded options are available, so you aren't locked into one or the other. Coaching comes with the program rather than as an add-on.

What you'll pay at Joi + Blokes

  • Compounded semaglutide: $99 to start, then $179/mo
  • Compounded tirzepatide: $149 to start, then $249/mo
  • Brand-name tirzepatide — Zepbound 2.5 mg vial plus the $99 program: $448/mo

The typical price we see is about $196/month, so Joi + Blokes is in the middle of the pack. Over a year at that rate, you'd spend about $2,148. The price is the same at every dose, so the bill doesn't grow as you step up.

What's included: the clinician consult, the medication, and coaching.

What Joi + Blokes prescribes

Joi + Blokes prescribes semaglutide and tirzepatide. Semaglutide is the drug in Wegovy and Ozempic; tirzepatide, the drug in Zepbound and Mounjaro, also acts on GIP and is often preferred where insulin resistance drives weight. It can also prescribe FDA-approved brand pens, which come with the manufacturer's pregnancy and breastfeeding labeling — a cleaner document to take to your OB.

Getting started

It doesn't treat patients in every state, so check yours first.

How Joi + Blokes compares

Close in price to Joi + Blokes, and worth comparing:

  • Heros Health — $179/mo, semaglutide and tirzepatide, same price at every dose
  • NativeMed — $179/mo, semaglutide and tirzepatide, same price at every dose
  • Sprout Health — $299/4 wks, semaglutide and tirzepatide, same price at every dose

Where Joi + Blokes fits — and where it doesn't — for mothers

Worth a look if…

  • You'd like a real prescriber looking at your health history before anything ships.
  • The monthly bill is what decides it, and you want a low, predictable number.
  • You may want to switch between semaglutide and tirzepatide later on.
  • You want coaching alongside the prescription.

Probably not for you if…

  • A clean regulatory record is a dealbreaker — it has an FDA warning letter, covered in the cons above.
  • You need a no-strings plan; the cancellation fine print here is worth reading before you sign up.
  • You're breastfeeding or trying to conceive and want a prescriber to weigh in on timing — see CoreAge Rx, a featured partner.

Trust, safety, and oversight

Joi + Blokes has an FDA warning letter on its record; it's summarized in the cons, and it's worth reading before you start. Before you start, ask which licensed pharmacy compounds your medication and what the formulation contains. Our methodology shows how oversight feeds the score.

Tell your own clinician if you are pregnant, breastfeeding or trying to conceive before starting treatment. Using medication for weight loss is not recommended while pregnant. Breastfeeding decisions require the specific product’s labeling and an individual assessment, rather than a blanket rule across every GLP-1 formulation.

Before you pay, ask

  • What does the price become after the first month?
  • How do I cancel, and is there a minimum term?
  • What happens to my plan if I become pregnant?

Our take

We list Joi + Blokes with its FDA warning letter in plain view; weigh that first. If you're still choosing, compare it with CoreAge Rx, a featured partner.

The bottom line for mothers

Best for: A woman in her 40s whose weight shifted alongside hormone or thyroid changes, who wants GLP-1 care and hormone care from one company and can commit to three months.

Alternatives to Joi + Blokes

These are partners — we may be paid if you sign up through these links. The full list has every provider we cover, partner or not.

  • CoreAge RxFeatured partner

    The one program on our list whose number still makes sense at the top of the dose. A flat, all-in monthly price on both molecules, no teaser rate to expire, and a cancel button you can actually find — the closest thing to a family-budget guarantee we've reviewed.

    Visit CoreAge Rx
  • Luvo Health publishes a standing price for every program before asking you for anything, and sells almost everything: semaglutide as an injection at $209 or tablets at $259, tirzepatide at $249, a low-dose microdosing tier at $179, and real FDA-approved Ozempic and Zepbound at $1,299 and $1,399 for anyone who wants the on-label product — all per four weeks, with the first four weeks half price on the main programs. Its LegitScript certification is real — the seal ID returns a live image where an invented one errors — and it commits to not charging you if a clinician decides you aren't eligible. Two things hold it back. It never names the pharmacy that compounds any of this, which is a step behind the providers that do.

    Visit Luvo Health
  • The highest-paying program on our list advertises a prepaid rate as if it were the price, promises a flat dose price its own help center contradicts, and bills every 28 days whether or not the medicine arrives. The blog on nursing is better than the company behind it.

    Visit ShedRx

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Joi + Blokes, answered

Is it really cancel-anytime?
Not at the start. The product page says you can adjust or cancel anytime, but the Terms you agree to set a minimum of three consecutive months on subscriptions, and plans are billed quarterly. Plan on paying for the first three months either way.
What is the FDA warning letter about?
In June 2026 the FDA wrote to Joi + Blokes about false or misleading claims on its website about compounded semaglutide and tirzepatide. The letter is about how the products were marketed, not a finding that a specific batch was unsafe, and the company is still selling.
Is this program just for women?
No. Joi is the women's side and Blokes is the men's, under one company. The women's side also sells hormone therapy, thyroid care and lab panels, which is useful if your weight changes came with perimenopause or thyroid questions.
Do I need labs first?
No. Joi + Blokes says labs are not required for GLP-1 care but are available if you want a fuller picture. Lab panels are sold separately.

Pricing, states and verification reflect Joi + Blokes's public disclosures at last review; the Editors' Rating is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.

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