Defy Medical review
Defy Medical is a Tampa hormone clinic that has run telehealth care for more than a decade, and it now prescribes semaglutide, tirzepatide and liraglutide everywhere except Mississippi. It works the old-fashioned way: a paid weight-management consult, a required metabolic lab panel, then medication ordered and paid for one order at a time, with no subscription. That suits a mother who wants real lab work and her hormones looked at alongside her weight, but it leaves her budgeting blind, because no current price for the medication appears anywhere on its site.
- Six-factor Editors' Rating
- Source-based review
This review draws on the provider’s public pricing, terms and disclosures. No one on this desk is your clinician.
Defy Medical at a glance
- Semaglutide
- Not published before a paid consult
- Tirzepatide
- Not published before a paid consult
- Coverage
- All states except Mississippi
- Brand-name
- Compounded only
How we scored Defy Medical
Each score comes out of Defy Medical's published pricing, disclosures and oversight, and the six combine into the 60/100 Editors' Rating on our weighted six-factor framework. A commission never changes a provider's score.
Cost is unpredictable, premium, or hides behind a plan commitment.
Reasonable oversight, though some program details aren't fully public.
The headline rate obscures a plan requirement or a hidden step-up.
Little here is shaped around a mother's week or her life stage.
Support is thin once the prescription ships.
Leaving costs you — notice windows, minimum terms or fees you don't get back.
How we verified this review
- Primary source
- The company's own site
Defy Medical is a long-running hormone clinic that prescribes semaglutide, tirzepatide and liraglutide by telehealth in every state but Mississippi. It requires a metabolic lab panel and a paid consult before any prescription and bills each service separately, with no subscription — but it publishes no current price for the medication itself.
What we like
- Required lab work at the start, three months in and every six months after
- No subscription or contract — you pay per consult, panel and order
- Women's hormone therapy and menopause care under the same roof
- Semaglutide, tirzepatide and liraglutide, with injection and non-injection forms
- Telehealth in every state except Mississippi
The caveats
- No current price for GLP-1 medication is published; the only figures are in a 2023 handout
- Consults and lab panels are billed separately and recur every six months
- Consults are not refunded if no prescription is written, and a late cancellation can be charged in full
- Its dissolving tablets and drops are not FDA-approved forms of either medicine
- Does not accept insurance
- The clinic's main business is men's testosterone care, so women's weight care is one line among many
- Its GLP-1 pages say nothing about pregnancy, breastfeeding or postpartum timing
Defy Medical in short
Defy Medical doesn't post a standard monthly price, so you'll need a quote before you can compare it. Where it earns its score is clinical oversight. Where it loses ground is price transparency.
What you'll pay at Defy Medical
Defy Medical doesn't post a standard monthly cash price up front — pricing appears after an intake quiz. Get a written quote and confirm the ongoing rate before you commit.
The clinician consult and lab work are not included, so add those to the total.
The medications Defy Medical prescribes
Defy Medical prescribes a GLP-1 medication. These are compounded versions from a licensed pharmacy, which keeps the price down, but compounded GLP-1s are not FDA-approved finished products the way Wegovy and Zepbound are.
There's also an oral or under-the-tongue option for mothers who'd rather skip injections. Keep expectations modest: these forms have far less research behind them than the weekly shot.
Before you start the intake
It doesn't treat patients everywhere (All states except Mississippi), so check your state first.
Alternatives to Defy Medical
Other providers we've reviewed that offer a GLP-1 medication:
- LunaRx — no comparable monthly rate confirmed, semaglutide
- Eviora MD — no comparable monthly rate confirmed, semaglutide
- Curex — $199/mo, semaglutide
Who Defy Medical suits, and who should look elsewhere
A good fit if…
- You want a straightforward GLP-1 program and will confirm the details before you commit.
Look elsewhere if…
- You'd only consider Wegovy or Zepbound themselves, not a compounded version.
- You want to be able to cancel easily — read the cancellation terms in the cons first.
- You live outside its service area (All states except Mississippi).
- You want one flat price at every dose — compare CoreAge Rx, a featured partner.
Trust, safety, and oversight
It's fair to ask any compounded provider two things: which pharmacy makes the medication, and what's in it. Our methodology shows how oversight feeds the score.
Weight-loss treatment is not recommended during pregnancy. If you are breastfeeding or planning pregnancy, discuss the exact medicine, formulation and timing with your own clinician; limited milk-transfer data do not establish infant safety.
Questions to ask before you pay
- What will I pay each month, and does that change as the dose goes up?
- Does one billing period mean a calendar month or four weeks?
- How do I cancel, and is there a minimum term?
- Will I need lab work, and who pays for it?
- What happens to my plan if I become pregnant?
The bottom line
Without a posted monthly price, Defy Medical is hard to judge on cost. Its strongest point with us is clinical oversight; get a quote before you weigh it against the rest. CoreAge Rx, a featured partner, is worth a side-by-side look before you decide.
The bottom line for mothers
Best for: A mother in perimenopause who wants a lab-driven clinic to manage hormones and a GLP-1 together, and who will ask for every fee in writing first.
Alternatives to Defy Medical
These are partners — we may be paid if you sign up through these links. The full list has every provider we cover, partner or not.
- Visit CoreAge RxCoreAge RxFeatured partner
The one program on our list whose number still makes sense at the top of the dose. A flat, all-in monthly price on both molecules, no teaser rate to expire, and a cancel button you can actually find — the closest thing to a family-budget guarantee we've reviewed.
- Visit Oak
A flat, all-dose compounded price with an oral option and a genuinely thorough intake — undercut by a headline that isn't the real month-to-month number and terms that lock you in hard once the box ships.
- Visit MadeMed
A flat-rate compounded program with no dose-based price creep — $239/mo semaglutide, $399/mo tirzepatide on the standard quarterly plan — but it's only licensed in 23 states, so check the list before you get attached to the price.
Providers like Defy Medical
Keep comparing Defy Medical
Head-to-head & alternatives
Ranked boards
- The 2026 guide to the best GLP-1 for moms
- Best GLP-1 for women — PCOS & menopause
- Best GLP-1 for first-timers & beginners
- Cheapest GLP-1 without insurance
- Best GLP-1 after baby — postpartum providers ranked
- Best GLP-1 with insurance & coverage help
- Best GLP-1 providers for PCOS
- Best GLP-1 for perimenopause & menopause
- Cheapest tirzepatide online, month to month
- Cheapest semaglutide online, month to month
Defy Medical, answered
- How much does Defy Medical cost for GLP-1s?
- Defy does not post a current GLP-1 price. You pay separately for a weight-management consult, a metabolic lab panel and each medication order. A cost handout still on its site, written in 2023, listed a $69 consult, a $59 panel and semaglutide averaging under $250 a month at the top dose; ask what each costs today before you book. These are advertised figures; the recurring invoice amount and billing interval are unconfirmed in our current records. Confirm both before paying.
- Do I need labs?
- Yes. Defy requires a comprehensive metabolic lab panel before the first consult, another panel with a follow-up visit three months in, and then a consult and panel every six months. Budget for those as recurring costs, because they are billed on their own.
- Does Defy treat menopause and weight together?
- It can. Defy runs a women's hormone line with bioidentical hormone therapy and menopause care alongside its GLP-1 program, so one provider can look at both. The clinic is just as busy with men's testosterone care, so ask for a provider who focuses on women.
- Is there a subscription?
- No. Defy says there are no subscriptions or contracts; you pay for a consult, a lab panel or a medication order when you buy it. A consult canceled less than 24 hours ahead may be charged in full, and consults are not refunded if no prescription is written.
- Which forms of semaglutide and tirzepatide does it offer?
- Weekly injections, plus dissolving tablets and under-the-tongue drops of both medicines. The tablet and drop forms are not FDA-approved products, so ask your provider why one would suit you better than the weekly shot.
Pricing, states and verification reflect Defy Medical's public disclosures at last review; the Editors' Rating is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.