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Grade C

TMates review

Compounded semaglutide is $249 for a one-month plan and tirzepatide $297, with dose-independent pricing and oral options. Three-, six- and twelve-month plans show their larger totals. Current shipping FAQ says most states. Refunds stop once an approved prescription is written and transmitted to a pharmacy.

$249/mo
Flat price · every dose
Consult Medication
See plans at TMates
  • Six-factor Editors' Rating
  • Source-based review
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By Margaux Ellery, Editor-in-Chiefa mother on the MetabolicMoms desk, not a treating clinician

This review draws on the provider’s public pricing, terms and disclosures. No one on this desk is your clinician.

TMates at a glance

Semaglutide
$249/mo
Tirzepatide
$297/mo
Coverage
Most states per product FAQ; confirm selected treatment at your address
Brand-name
Compounded only

How we scored TMates

Each score comes out of TMates's published pricing, disclosures and oversight, and the six combine into the 66/100 Editors' Rating on our weighted six-factor framework. A commission never changes a provider's score.

Family-budget value60/100 · Weak

Cost is unpredictable, premium, or hides behind a plan commitment.

Clinical oversight & labs58/100 · Weak

Oversight and lab support fall short of the best we track — the review below says exactly where.

Pricing transparency85/100 · Strong

The core price is disclosed, but some conditions or add-ons aren't upfront.

Fits around motherhood66/100 · Weak

Little here is shaped around a mother's week or her life stage.

Ongoing support & titration62/100 · Weak

Support is thin once the prescription ships.

Flexibility to pause or cancel70/100 · Weak

Leaving costs you — notice windows, minimum terms or fees you don't get back.

How we verified this review

Primary source
The company's own site

Checked October 2026: one-month prices $249 semaglutide/$297 tirzepatide, same price at listed doses; prepaid total ladders $650/$1,050/$1,900 and $800/$1,299/$1,999. Current product FAQ says most states, and the tirzepatide page discusses pregnancy/nursing exclusions. Terms provide pre-review/ineligibility refunds but none after approved prescription transmission. No assigned pharmacy established.

Before you sign up

We opened TMates's signup and stopped at the first screen that asked for personal details, so we can't tell you what comes after it. Here's what's worth knowing before you start.

These signup observations are from . The flow and offers may have changed; use the current pricing and terms in this review.

Worth knowing

  • No monthly price is visible on the public homepage; the number appears only after you begin the intake

Pricing

MedicationPricePlan
Compounded semaglutide$249One-month injectable plan, same price at listed dosesCurrent live product page lists $249 for the one-month plan, including medication, support and free shipping. A separate 28-day invoice was not confirmed.
Compounded tirzepatide$297One-month injectable plan, same price at listed dosesCurrent live product page lists $297 for the one-month plan, without an introductory-only label. Confirm the actual renewal date and supply.
Oral semaglutide$249One-month compounded oral optionThe oral format selector retains the $249 one-month price. Compounded oral medication is not interchangeable with approved oral brands; obtain formulation-specific instructions.
Oral tirzepatide$297One-month compounded oral optionCurrent oral toggle retains $297. Its 0.25/0.5mg selector differs from injectable 2.5–15mg choices. These are seller options, not dosing advice or a bioequivalence claim.
Compounded semaglutide$216.67Three-month plan; $650 total$650 total; seller rounds equivalent to $217/mo.
Compounded semaglutide$175Six-month plan; $1,050 total$1,050 total; $175/month equivalent on larger commitment.
Compounded semaglutide$158.33Twelve-month plan; $1,900 total$1,900 total; seller rounds equivalent to $158/mo.
Compounded tirzepatide$266.67Three-month plan; $800 total$800 total; seller rounds equivalent to $267/mo.
Compounded tirzepatide$216.5Six-month plan; $1,299 total$1,299 total; seller rounds equivalent to $217/mo.
Compounded tirzepatide$166.58Twelve-month plan; $1,999 total$1,999 total; seller rounds equivalent to $167/mo.

Swipe the table to see plan details →

GLP-1 telehealth is usually HSA- and FSA-eligible, so check your own plan. Everything above comes from TMates's public disclosures at last review and change often; confirm the current number on TMates's own site.

What we like

  • Publishes one-month prices and longer-plan totals before intake
  • Same-price-at-listed-doses promise on both product pages
  • Injectable and compounded oral options with format prices visible
  • Medication, provider review, ongoing support and free delivery described in the offer

The caveats

  • Lower monthly equivalents require a larger plan commitment
  • No complete state list or assigned clinician/pharmacy established on the pages checked
  • Prescription transmission ends refund eligibility, and an unapproved refund leaves payment-plan obligations in place
  • Cancel-anytime wording does not publish a clear cutoff before the next pharmacy order
  • Compounded oral formats need their own formulation and dosing explanation; they are not approved-brand substitutes

TMates: the monthly option is clear, the refund cutoff matters

TMates publishes one-month compounded semaglutide at $249 and tirzepatide at $297, with the same price across listed doses. Longer prepaid plans lower the advertised monthly equivalent. Its more important limitation is the refund cutoff: once an approved prescription is written and sent to a pharmacy, the Terms say there is no refund.

Read the total beside the monthly equivalent

The semaglutide page lists $650 for three months, $1,050 for six and $1,900 for twelve. It displays rounded equivalents of $217, $175 and $158 per month. Tirzepatide totals are $800, $1,299 and $1,999, displayed as $267, $217 and $167 per month. These are larger plan commitments; the twelve-month figure is not an ordinary $158 or $167 single-month purchase.

The listed totals reconcile reasonably with the rounded averages and advertised savings. Nevertheless, a rounded monthly equivalent is a comparison aid, not the charge your bank will necessarily show. Request the complete payment schedule and renewal amount for the selected plan. Financing a larger total does not prove you can leave after one installment without further responsibility. The Terms expressly say a payment plan remains in place if a refund request is not approved.

The product pages use month labels and publish a one-month price. They do not establish a separate four-week invoice cycle or state exactly how many doses arrive in each shipment on every longer plan. Weekly administration and calendar billing are different details. Confirm the supply and next invoice date in your order, especially before a trip or a period when you may need to pause care.

Flat dose pricing does not settle formulation questions

The pages explicitly promise the same price at different listed doses. That makes a budget easier to understand than a starting figure followed by undisclosed increases. The injectable semaglutide selector spans 0.25mg to 2.4mg and injectable tirzepatide spans 2.5mg to 15mg. Those are available selector choices, not instructions to choose a dose yourself. Your clinician should determine the medication, concentration and titration, including what happens if the original plan changes.

Both pages also offer injectable and oral formats. A compounded oral option should not be treated as interchangeable with an approved oral brand, or presumed to share the same absorption, dosing schedule and evidence as an injection. The public descriptions lean heavily on weekly injection wording even though an oral option is selectable. Ask for the exact oral formulation, administration instructions and clinical rationale before choosing it for convenience. A pill preference deserves more than a format toggle.

Canceling future care and refunding an order are separate

The Terms allow a full refund before the medical team reviews the patient's history. They also provide a full refund after review if the patient does not qualify for a medication-assisted weight-loss plan. Once the patient qualifies and a prescription is written and sent to the pharmacy, the policy says no refund. This makes the pharmacy handoff the practical point to understand, rather than waiting until a box ships.

Product pages say cancel anytime, and the Terms permit account deactivation by email. They do not provide a clear advance cutoff for stopping the next medication order in the public sections read. Get that cutoff, the cancellation channel and written confirmation before accepting a recurring or longer commitment. Cancel anytime should not be read as permission to return dispensed medicine or erase remaining installments on a nonrefundable order.

The included care still needs named contacts

TMates describes provider review, personalized dosing, medication, ongoing support and free delivery. Its general FAQ also mentions telemedicine visits and coaching. These are useful inclusions to confirm on your selected order, including whether recommended laboratory testing creates a separate cost. The semaglutide FAQ says bloodwork is not always required but may be recommended from the medical history. That is a clinical decision, not an assurance that every patient can skip testing.

The doctors page makes broad claims about U.S.-based board-certified physicians and training, but does not identify the clinician assigned to your prescription. The public pages checked also do not name the dispensing pharmacy. Ask for both contacts and the pharmacy's instructions before fulfillment. TMates says it is not itself a compounding facility and that compounded medications are not evaluated by FDA for safety, quality or effectiveness. Generic credential or quality language does not establish FDA approval of a finished compounded prescription.

Coverage and pregnancy planning need direct confirmation

The homepage describes doctor access in all fifty states, while the semaglutide product FAQ says shipping reaches most states and depends on eligibility. We do not turn a nationwide physician-network claim into a promise that every product ships everywhere. Confirm your physical location and selected medication before payment. The service's online convenience also does not establish a clinical response-time guarantee, despite broad access language.

The current tirzepatide page explicitly excludes pregnancy and breastfeeding and says it should not be used while trying to conceive. A mother's recent delivery, nursing, contraception and future pregnancy plans should be part of the actual medical assessment. No dedicated postpartum or PCOS protocol was established from the pages read. Our postpartum timing guide can help prepare the questions.

Our decision point

TMates is relatively easy to compare on advertised monthly and prepaid amounts, with an explicit dose-independent price promise. The remaining questions are practical: which clinician and pharmacy, what supply and renewal, and what cancellation deadline before prescription transmission? Resolve those before committing a larger sum. This review uses current public information, not patient experience or a completed intake.

The bottom line for mothers

Best for: Mothers comparing an explicit one-month price with prepaid plans, after confirming formulation, dispensing pharmacy and refill cancellation timing.

Alternatives to TMates

These are partners — we may be paid if you sign up through these links. The full list has every provider we cover, partner or not.

  • CoreAge RxFeatured partner

    The one program on our list whose number still makes sense at the top of the dose. A flat, all-in monthly price on both molecules, no teaser rate to expire, and a cancel button you can actually find — the closest thing to a family-budget guarantee we've reviewed.

    Visit CoreAge Rx
  • Semaglutide is $199 a month as either the weekly shot or a daily pill, tirzepatide is $299 bundled with B12 and glycine, and the price does not climb as your dose goes up. Every plan includes a smart scale that separates fat from muscle, which is a better question than the one your bathroom scale answers. Two things deserve a slow read before you buy. Nothing on the public site carries a price until you have handed over your height, weight and date of birth. And the money-back promise in the homepage banner is not the promise written into the terms — the banner refunds you for missing 10% in six months, the contract refunds you only if you lose nothing at all in 90 days.

    Visit HumeCare+
  • A flat $249/mo semaglutide, $299/mo tirzepatide after a $99 first month, with an option most of the providers we list skips: a sublingual tablet instead of a weekly shot — but the FDA issued its parent entity, Lean Rx, Inc., a warning letter on 02/20/2026 (ref. 717989) for mislabeling itself as the compounder on its own product images and for marketing language implying its compounded products share FDA-approved status with Mounjaro and Zepbound, which they don't. Confirmed directly on FDA.gov; SkinnyRx's own site never mentions it.

    Visit SkinnyRx

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TMates, answered

What does one month of TMates cost?
Current product pages list $249 for semaglutide and $297 for tirzepatide, with the same price at listed doses. Lower equivalents belong to longer plans with larger totals. Confirm the actual supply and renewal date; a distinct four-week invoice was not established.
How much must I pay for a longer TMates plan?
Semaglutide totals are $650 for three months, $1,050 for six and $1,900 for twelve. Tirzepatide totals are $800, $1,299 and $1,999. Rounded monthly equivalents do not make these independent monthly purchases.
Can TMates refund my medication order?
Terms provide a full refund before medical-history review and if the reviewed patient does not qualify. Once an approved prescription is written and transmitted to pharmacy, there is no refund. If a refund is not approved, payment-plan obligations remain.
Does TMates ship to all fifty states?
The current semaglutide FAQ says most states and eligibility-dependent shipping. The homepage makes a broader nationwide doctor-access statement. Confirm the selected treatment at your location rather than assuming every product is available everywhere.
Does TMates discuss pregnancy and breastfeeding?
Yes. Its current tirzepatide page excludes pregnancy and breastfeeding and says it should not be used while trying to conceive. Discuss nursing, contraception and pregnancy timing with the actual prescriber; a dedicated postpartum program was not established.

Pricing, states and verification reflect TMates's public disclosures at last review; the Editors' Rating is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.

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