He and She MD review
A broad compounded-plus-brand menu with seven real price points — $199/mo standard semaglutide down to $99/mo on the 12-month plan — though nearly every itemized figure is the annual-prepay rate, and tirzepatide's standard monthly cost isn't published.
Every medical claim in this piece is footnoted to the record it came from — the trial or the FDA label — so you can read the source rather than take the masthead's word for it. No one on this desk is your clinician.
He and She MD at a glance
- Semaglutide
- $199/mo standard (injectable), $99/mo on the 12-month plan
- Tirzepatide
- $159/mo on the 12-month plan; standard monthly rate not itemized on the page checked
- Coverage
- All 50 states
- Brand-name
- Yes
How we scored He and She MD
Each factor is scored from He and She MD's real pricing, disclosures and oversight, then combined into the 58/100 Editors' Rating by the same weighted six-factor framework we apply to every provider — never nudged by whether a provider pays us.
Cost is unpredictable, premium, or hides behind a plan commitment.
Limited public detail on who oversees care and how.
The headline rate obscures a plan requirement or a hidden step-up.
Little here is shaped around a mother's week or her life stage.
Support is thin once the prescription ships.
Leaving costs you — notice windows, minimum terms or fees you don't get back.
How we verified this review
- Last verified
- August 2026
- Confidence
- medium
- Primary source
- heandshemd.com
Sourced from WLR's provider directory, independently re-verified live on heandshemd.com (2026-08-02). Seven price points confirmed on the weight-loss page, each explicitly marked as a 12-month-supply rate. The homepage banner separately references '$199/month' for injectable semaglutide as the 'from' price before the 12-month discount — treated as the standard month-to-month rate here. No equivalent standard-rate reference was found for tirzepatide.
What to expect when you sign up
We walked He and She MD's public signup funnel (August 2026) — a first-hand look at the flow. We don't create accounts, enter medical data, or complete checkout, so this is what any visitor sees, not a patient outcome.
- 1The homepage lists seven real price points across compounded, oral, and brand forms of both molecules, all marked as 12-month-plan rates, no intake required to see the numbers
- 2A 5-minute quiz determines eligibility; a licensed U.S. clinician reviews before anything is prescribed
- 3The site states 'no hidden fees, ever' and free expedited shipping on every order
What we noticed
- A genuinely broad menu — compounded injectable, compounded oral, and FDA-approved brand (Ozempic, Zepbound) for both molecules, all priced — but every itemized figure is explicitly the 12-month-prepay rate, and only semaglutide's standard month-to-month rate ($199) is referenced, in the banner rather than the pricing table itself
- Tirzepatide's standard (non-annual-prepay) monthly rate was not found on the pages checked
- No named compounding pharmacy or medical director found on the pages checked, and no statement on video-visit requirements
Pricing
Prices re-verified
| Medication | Monthly | Plan |
|---|---|---|
| Compounded semaglutide | $199 | Injectable, standard monthlyReferenced in the homepage banner as the 'from' price before the 12-month-plan discount. |
| Compounded semaglutide | $99 | Injectable, 12-month planListed as '$99/month*' — the asterisk notes this is the price for a 12-month supply purchase. |
| Oral semaglutide | $209 | Oral, 12-month plan12-month prepaid rate; standard monthly rate not itemized on the page checked. |
| Brand semaglutide | $1299 | Ozempic®, 12-month plan12-month prepaid rate. |
| Compounded tirzepatide | $159 | Injectable, 12-month plan12-month prepaid rate; standard monthly rate not itemized on the page checked. |
| Oral tirzepatide | $269 | Oral, 12-month plan12-month prepaid rate. |
| Brand tirzepatide | $1399 | Zepbound®, 12-month plan12-month prepaid rate. |
Swipe the table to see plan details →
HSA/FSA is commonly accepted for GLP-1 telehealth — check your plan. Prices reflect He and She MD's public disclosures at last review and change often; confirm the current number on He and She MD's own site.
What we like
- A genuinely broad menu — compounded injectable, compounded oral, and FDA-approved brand (Ozempic, Zepbound) for both molecules, all on one platform
- Seven real price points visible directly on the site, no intake required to see them
- States 'no hidden fees, ever' and free expedited shipping on every order
- A 5-minute quiz with licensed clinician review, described as a fast intake path
The caveats
- Nearly every itemized price is the 12-month-prepay rate — the standard month-to-month cost is only referenced for semaglutide ($199/mo), not tirzepatide
- No named compounding pharmacy or medical director found on the site
- No published time-to-first-dose or statement on whether a video visit is required
- Brand pricing ($1,299-$1,399/mo) is a steep jump from the compounded tiers — confirm which you're selecting before checkout
He and She MD for mothers: our verdict
A broad compounded-plus-brand menu with seven real price points — $199/mo standard semaglutide down to $99/mo on the 12-month plan — though nearly every itemized figure is the annual-prepay rate, and tirzepatide's standard monthly cost isn't published. It runs about $99/month, flat across every dose — toward the affordable end of what we track.
We weigh He and She MD the way mothers actually have to: not just the real monthly cost, but the real monthly cost once the dose climbs and whether a real clinician stands behind it — the parts a generic weight-loss review skips.
What He and She MD actually costs
- Compounded semaglutide — Injectable, standard monthly: $199/mo
- Compounded semaglutide — Injectable, 12-month plan: $99/mo
- Oral semaglutide — Oral, 12-month plan: $209/mo
- Brand-name semaglutide — Ozempic®, 12-month plan: $1299/mo
- Compounded tirzepatide — Injectable, 12-month plan: $159/mo
- Oral tirzepatide — Oral, 12-month plan: $269/mo
That sits below the roughly $149 median ongoing price across the providers we track for mothers — a real cost advantage.
The medications He and She MD prescribes
He and She MD prescribes semaglutide and tirzepatide — the two molecules with the strongest published weight-loss outcomes, and having both on one account matters when insulin resistance (common with PCOS and after gestational diabetes) makes tirzepatide the better-suited option. It can route you to FDA-approved brand pens as well as compounded versions — the on-label products carry the manufacturer's own pregnancy and lactation labeling, which is cleaner to hand to an OB.
A needle-free oral or sublingual option is on the menu, which draws in mothers who've been avoiding injections — just set expectations: oral and buccal delivery of these peptides is far less studied than the injectable versions the trials used.
Where He and She MD fits — and where it doesn't — for mothers
A good fit if…
- you want a real clinician reading your history around the real monthly cost once the dose climbs, not an auto-approving quiz.
- the real monthly cost is a real barrier and you want a low, predictable number.
- you may need to move between semaglutide and tirzepatide as your body and hormones change.
- uninterrupted nationwide access matters — a move for family shouldn't interrupt care.
Look elsewhere if…
- you'd rather a prescriber talk through timing around the real monthly cost once the dose climbs — that's what our #1 pick, CoreAge Rx, is built for.
Trust, safety, and oversight
Our confidence is moderate — the core facts check out, but some details (per-state availability, program mechanics) aren't fully public. As with any compounded GLP-1, the most useful thing mothers can do is confirm which licensed pharmacy fills the prescription and what's in the formulation — we explain how we weigh oversight in our Editors' Rating methodology.
A standing caveat for mothers: GLP-1 medications aren't established as safe during pregnancy or breastfeeding, and every label advises against use. Nothing here changes that — plan the timing with your own clinician.
The bottom line
He and She MD is a genuine value play — weigh it on the real monthly cost once the dose climbs and whether a real clinician stands behind it against the alternatives below. For most mothers, CoreAge Rx remains the stronger all-round fit — see why it tops our ranking.
The bottom line for mothers
Best for: Mothers comfortable committing to a 12-month prepaid plan to reach the lowest advertised prices, and who want brand-name options on the same platform.
Alternatives to He and She MD
Providers we have a referral relationship with, ordered by their Editors' Rating — highest first. A fee never moves a rating, but it does decide who appears here, so this is not the whole roster: the full ranking lists every provider we cover.
- Visit CoreAge RxCoreAge RxOur #1 pick
The one program on this masthead whose number still makes sense at the top of the dose. A flat, all-in monthly price on both molecules, no teaser rate to expire, and a cancel button you can actually find — the closest thing to a family-budget guarantee we've reviewed.
- Visit Gala Health
A flat $179 for either molecule and a genuinely gentle microdosing tier — a reasonable, all-doses-included option, if you can live with a yearly plan and a pharmacy the marketing never names.
- Visit Sesame
A high-trust telehealth marketplace that took a clear side: FDA-approved brand GLP-1 only, no compounded shortcut. You pay a brand cash price and book a real video visit — but you get on-label pens and one of the cleaner reputations on this masthead.
Keep comparing He and She MD
Head-to-head & alternatives
He and She MD, answered
- How much does He and She MD cost?
- As last verified, He and She MD's compounded pricing starts around $99/month ($199/mo standard (injectable), $99/mo on the 12-month plan semaglutide, $159/mo on the 12-month plan; standard monthly rate not itemized on the page checked tirzepatide). Confirm the current, all-in price on He and She MD's own site before you commit.
- Is He and She MD safe to use while breastfeeding?
- No GLP-1 — compounded or brand — is established as safe during pregnancy or breastfeeding, and the labels advise against use; He and She MD is no exception. Plan any GLP-1 for after weaning, and discuss the timing with your own clinician.
- Does He and She MD offer both semaglutide and tirzepatide?
- Yes — He and She MD offers both molecules. Tirzepatide's dual GIP/GLP-1 action is often preferred where insulin resistance drives weight, which matters for PCOS and after gestational diabetes.
- Where does He and She MD rank for mothers?
- He and She MD scores 58/100 on our Editors' Rating (rank #59), which weights six factors that matter for mothers. Our #1 pick, CoreAge Rx, leads the ranking — see how they compare.
Pricing, states and verification reflect He and She MD's public disclosures at last review; the Editors' Rating is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.