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Head-to-head for moms

CoreAge Rx vs Ryze Rx

For semaglutide, CoreAge Rx is the cheaper of the two at the first dose: $99 against $119 a month. Choose CoreAge Rx if you want the lower semaglutide price. The details, from each provider's own published prices and terms, are below.

CoreAge Rx

Higher score

Editors' Rating 94/100 · Grade A

Best for: Mothers who want to know the real monthly cost before the free trial talks them into it — one flat price on semaglutide or tirzepatide, everywhere in the country, with no lock-in.

Visit CoreAge Rx
vs

Ryze Rx

Editors' Rating 31/100 · Grade C

Best for: A Spanish-speaking reader who values the bilingual intake and will ask how long each vial lasts before buying.

Visit Ryze Rx

The verdict

Higher Editors' Rating: CoreAge Rx

CoreAge Rx edges out Ryze Rx on the Editors' Rating, 94 to 31 (A vs C). Mothers who want to know the real monthly cost before the free trial talks them into it — one flat price on semaglutide or tirzepatide, everywhere in the country, with no lock-in.

Ryze Rx is still a genuine option — ryze Rx now prices compounded GLP-1s by the vial: semaglutide runs from $119 for a 1 mg vial to $219 for a 10 mg vial, and tirzepatide from $199 for a 5 mg vial to $359 for 30 mg, with three-month tirzepatide kits at $499 and $799. What it doesn't say is how long each vial lasts at your dose, so the monthly cost is yours to work out with the clinician. The homepage still argues with itself — "GLP-1s from $119/mo" in the header, "From $149/mo" on the card below — but the site is fully bilingual, English and Spanish, which matters more than it usually gets credit for. Weigh the six factors below against your own priorities.

Side-by-side on the six factors

Each side's six factor scores from our women's-health rubric; the higher side on each factor is marked. See the methodology.

CoreAge Rx Ryze Rx
Family-budget value9522
CoreAge
Ryze
Clinical oversight & labs9034
CoreAge
Ryze
Pricing transparency9740
CoreAge
Ryze
Fits around motherhood9434
CoreAge
Ryze
Ongoing support & titration9228
CoreAge
Ryze
Flexibility to pause or cancel9532
CoreAge
Ryze

What CoreAge Rx and Ryze Rx cost

On semaglutide, CoreAge Rx charges $99 a month at every dose; Ryze Rx charges from $119 a month. CoreAge Rx is $20 a month cheaper, about $240 over a year.

On tirzepatide, CoreAge Rx charges $149 a month at every dose. Ryze Rx doesn't sell tirzepatide month to month: its lowest figure, $166 a month, comes with a longer commitment (3-month kit, 5 mg / 10 mg / 15 mg vials), so the two prices are not like for like.

CoreAge Rx vs Ryze Rx: price, access and signup
DetailCoreAge RxRyze RxDifference
Semaglutide, first dose$99$119CoreAge Rx $20 less
Tirzepatide, first dose$149$166 on a longer plan—
Brand-name medicationNoNo—
Included in the priceClinician consult, medication and shippingClinician consult and medication—
Price shownBefore intakeBefore intake—
Live video visitNot requiredNot required—
Oral optionNoNo—
Where it servesAll 50 states"Licensed providers in all 50 states"; no list published—
Editors' Rating94/10031/100CoreAge Rx +63

What the price covers

CoreAge Rx's price includes the clinician consult, the medication and shipping. Ryze Rx's price includes the clinician consult and the medication. So the sticker prices cover different things: shipping at CoreAge Rx but not, or not stated, at Ryze Rx. Add the missing pieces before you compare totals.

Where they serve and how signup works

Where they serve: CoreAge Rx, all 50 states; Ryze Rx, "Licensed providers in all 50 states"; no list published.

CoreAge Rx and Ryze Rx both show the price before the health questions. Neither CoreAge Rx nor Ryze Rx requires a live video visit; both start with an online questionnaire.

CoreAge Rx or Ryze Rx: who each one fits

Choose CoreAge Rx if…

  • You want the lower semaglutide price: $99 a month against $119 at Ryze Rx.
  • You want to pay for tirzepatide month to month rather than commit to a longer plan at Ryze Rx.
  • You want shipping included in the price, which Ryze Rx doesn't state.
  • You go by our Editors' Rating: 94/100 against Ryze Rx's 31.
Our CoreAge Rx review →

Choose Ryze Rx if…

  • In what both publish, Ryze Rx has no clear edge over CoreAge Rx on price, access or signup; read our Ryze Rx review for what it does differently.
Our Ryze Rx review →

CoreAge Rx

Editors' Rating 94/100 · Grade A

What we like

  • Flat all-in price that doesn't step up after month one — the number you sign for is the number at the full dose
  • Both compounded semaglutide and tirzepatide on a single account, so a molecule switch never resets the budget
  • Licensed in all 50 states — care survives a move, a deployment, or a summer at the grandparents'

The caveats

  • Not the rock-bottom sticker price — a bare teaser tier elsewhere can look cheaper for exactly one month
  • Compounded only; no FDA-approved brand Wegovy or Zepbound if that is what you and your clinician want
  • A general metabolic program, not a dedicated women's or maternal-health clinic

Ryze Rx

Editors' Rating 31/100 · Grade C

What we like

  • Fully bilingual, with an English and Spanish toggle throughout
  • Names its operating entity, Ryze RX LLC
  • Separates weight loss, testosterone and peptide lines rather than selling one plan

The caveats

  • Prices are per vial, and the site never says how many weeks a vial lasts at a given dose, so the true monthly cost isn't printed
  • The cost climbs with the dose: semaglutide from $119 to $219 a vial, tirzepatide from $199 to $359
  • The homepage contradicts itself — "GLP-1s from $119/mo" in the header against "From $149/mo" on the card below, and testosterone $89 against $99

CoreAge Rx vs Ryze Rx: quick answers

Is CoreAge Rx cheaper than Ryze Rx?

On standing month-to-month prices, for semaglutide, CoreAge Rx is cheaper at the first dose ($99 vs $119 a month). Promotions and prepaid plans are left out because the price you keep paying is the one that matters.

Do CoreAge Rx and Ryze Rx both offer tirzepatide?

Yes. CoreAge Rx lists tirzepatide at $149 a month at every dose, and Ryze Rx lists it at $166 a month on a longer plan.

Do I need a video visit with CoreAge Rx or Ryze Rx?

CoreAge Rx starts with an online questionnaire instead and Ryze Rx starts with an online questionnaire instead. Either way, a licensed clinician reviews your health history before anything is prescribed.

Do CoreAge Rx and Ryze Rx serve every state?

CoreAge Rx lists all 50 states. Ryze Rx lists "Licensed providers in all 50 states"; no list published. Both say they cover all 50, so where you live won't decide this one.

We may earn a referral fee if you sign up through a link on this page, at no extra cost to you. CoreAge Rx is a featured partner, and providers we work with may appear first. Scores are our own. Pricing, states and signup details reflect each provider's own published terms; the Editors' Rating is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing CoreAge Rx and Ryze Rx against other providers we review for mothers.

Or browse the full comparison hub.